top of page

Find out more about Sara

I am Dr. Sara D'Imperio, nutritionist biologist and researcher . I got my bachelor's degree from the University of Milan and my master's degree from the University of California . I also did my PhD in biochemistry on Brugada syndrome at the University of Milan. I later got two masters in human nutrition.  When I started my university career, I always had one purpose: to help people . During my university career I have done research in a variety of areas including female fertility, diabetes and heart disease.

In particular, during my PhD I specialized in Brugada syndrome,  for this reason I particularly want to put my knowledge and experience at the service of the community to improve, through nutrition,  the quality of life of anyone suffering from vascular diseases, autoimmune diseases or simply wanting to pursue a healthier lifestyle and feel better about themselves.  As with all cardiovascular and non-cardiovascular diseases, proper nutrition is the key to improving the quality of one's life. Establishing a healthy relationship with food is crucial for both you and your family.

My studies in America

In 2016 I received my master's degree from the prestigious University of California Irvine . My thesis was focused on the "Evaluation of vascular network formation in pancreatic extracellular matrix". I used a vascularized micro-organ-a-chip to evaluate the formation and function of the vascular network in the specific pancreatic extracellular matrix (ECM) within a 3D environment, emulating the native pancreas. The interdisciplinary nature of my studies has allowed me to gain proficiency with a variety of laboratory analytical techniques and cell biology techniques such as human primary cell propagation, e.g. human endothelial progenitor cells and fibroblasts. I also acquired skills in the manufacture of micro-fluid devices.

After my studies I worked as an Associate Scientist for Lattice Biologics, a start-up based in Scottsdale, Arizona . I developed 3D supports with human extra cellular matrix with the aim of mimicking the tissue micro environment to expand human derived stem cells. I am co-author of a patent we filed in February 2017 entitled "Methods of Processing Biological Liquid Allografts and Methods of Use" . This product called AmnioBoost ™ is a minimally processed amniotic fluid supplement for the treatment of joint pain associated with osteoarthritis.

I contributed to the development of production processes and to the composition of SOPs. On a weekly basis, I performed biochemistry and molecular biology tests such as Western Blot, protein quantification, SDS electrophoresis, DNA extraction and quantification, and PCR.

Laurea università Irvine Sara D'Imperio.jpg

The PhD in biochemistry

In 2020 I obtained my PhD in Biochemistry from the Department of Biotechnology and Translational Medicine
at the University of Milan Stem Cells Laboratory for tissue engineering, IRCCS Policlinico San Donato and Vita-Salute San Raffaele University.
I have studied the physiology, molecular biology, pharmacology and genetics of cardiac arrhythmias, with a particular focus on Brugada syndrome . I used patient / family data for scientific research purposes in order to better understand the mechanism of cardiac arrhythmias and why the molecular mechanisms differ between families. I used genetic information from patients to study the effects of specific mutations in the laboratory. 

Research activity

foto laboratorio San Donato.JPG

From left: Dr. Sara D'Imperio, Dr. Emanuele Micaglio, Dr. Michelle Monasky

In addition to the activity of biologist and Nutritionist I am a clinical researcher at the  Department of Arrhythmology and Electrophysiology, IRCCS Policlinico San Donato  directed by Prof. Carlo Pappone
I study the impact that nutrition and eating habits can have on the development of cardiac arrhythmias as well as on overall cardiovascular health and well-being. Furthermore, I also specifically study the role of genetics in relation to various eating habits. The goal is to better understand how patients can improve their eating habits in order to minimize the risk of cardiovascular disease and how to adapt diets to the specific needs of each individual. To do this, I use the most up-to-date studies and research.

Pubblicazioni scientifiche


The Mechanism of Ajmaline and thus Brugada Syndrome: Not Only the Sodium Channel

Monasky MM, Micaglio E,  D'Imperio S , Pappone C.

Front. Cardiovasc. Med., 2021 Nov 29;

DOI: 10.3389 / fcvm.2021.782596

Brugada Syndrome: Warning of a Systemic Condition?

D'Imperio S , Monasky MM, Micaglio E, Ciconte G, Anastasia L, Pappone C.

C.Front Cardiovasc Med. 2021 Oct 15;

8: 771349. doi: 10.3389 / fcvm.2021.771349. eCollection 2021.

PMID: 34722688 

Impact of Dietary Factors on Brugada Syndrome and Long QT Syndrome.

D'Imperio S , Monasky MM, Micaglio E, Negro G, Pappone C.

Nutrients. 2021 Jul 21;


13 (8): 2482. doi: 10.3390 / nu13082482.


PMID: 34444641 

Early Morning QT Prolongation During Hypoglycemia: Only a Matter of Glucose?

D'Imperio S , Monasky MM, Micaglio E, Negro G, Pappone C.


Front Cardiovasc Med. 2021 May 11; 8: 688875. doi: 10.3389 / fcvm.2021.688875. eCollection 2021.


PMID: 34046442 

Novel SCN5A p.Val1667Asp Missense Variant Segregation and Characterization in a Family with Severe Brugada Syndrome and Multiple Sudden Deaths.

Monasky MM, Micaglio E, Ciconte G, Rivolta I, Borrelli V, Ghiroldi A,  D'Imperio S , Binda A, Melgari D, Benedetti S, Mitrovic P, Anastasia L, Mecarocci V, Ćalović Ž, Casari G, Pappone C.

Int J Mol Sci. 2021 Apr 29; 22 (9): 4700. doi: 10.3390 / ijms22094700.

PMID: 33946750 

The antithetic role of ceramide and sphingosine-1-phosphate in cardiac dysfunction.

Cirillo F, Piccoli M, Ghiroldi A, Monasky MM, Rota P, La Rocca P, Tarantino A, D'Imperio S , Signorelli P, Pappone C, Anastasia L.

J Cell Physiol. 2021 Jul; 236 (7): 4857-4873. doi: 10.1002 / jcp.30235. Epub 2021 Jan 11.

PMID: 33432663

Brugada syndrome genetics is associated with phenotype severity.

Ciconte G, Monasky MM, Santinelli V, Micaglio E, Vicedomini G, Anastasia L, Negro G, Borrelli V, Giannelli L, Santini F, de Innocentiis C, Rondine R, Locati ET, Bernardini A, Mazza BC, Mecarocci V, Ćalović Ž, Ghiroldi A, D'Imperio S , Benedetti S, Di Resta C, Rivolta I, Casari G, Petretto E, Pappone C.

Eur Heart J. 2021 Mar 14; 42 (11): 1082-1090. doi: 10.1093 / eurheartj / ehaa942.

PMID: 33221895 

Role of sialidase Neu3 and ganglioside GM3 in cardiac fibroblasts activation.

Ghiroldi A, Piccoli M, Creo P, Cirillo F, Rota P, D'Imperio S , Ciconte G, Monasky MM, Micaglio E, Garatti A, Aureli M, Carsana EV, Menicanti L, Pappone C, Anastasia L.

Biochem J. 2020 Sep 18; 477 (17): 3401-3415. doi: 10.1042 / BCJ20200360.

PMID: 32869836 

Comparable clinical characteristics in Brugada syndrome patients harboring SCN5A or novel SCN10A variants.

Monasky MM, Micaglio E, Vicedomini G, Locati ET, Ciconte G, Giannelli L, Giordano F, Crisà S, Vecchi M, Borrelli V, Ghiroldi A, D'Imperio S , Di Resta C, Benedetti S, Ferrari M, Santinelli V , Anastasia L, Pappone C.

Europace. 2019 Oct 1; 21 (10): 1550-1558. doi: 10.1093 / europace / euz186.

PMID: 31292628

SCN5A Nonsense Mutation and NF1 Frameshift Mutation in a Family With Brugada Syndrome and Neurofibromatosis.

Micaglio E, Monasky MM, Ciconte G, Vicedomini G, Conti M, Mecarocci V, Giannelli L, Giordano F, Pollina A, Saviano M, Crisà S, Borrelli V, Ghiroldi A, D'Imperio S , Di Resta C, Benedetti S , Ferrari M, Santinelli V, Anastasia L, Pappone C.

Front Genet. 2019 Feb 15; 10: 50. doi: 10.3389 / fgene.2019.00050. eCollection 2019.

PMID: 30828344 


Dr. Sara D'Imperio

Sara D'Imperio as a qualified  and nutritionist biologist helps clients in the Novara, Borgomanero and province areas to live life in a healthier way. In addition to his doctorate in biochemistry, he obtained two masters in nutrition.

Provides nutritional advice for:

  • Children 

  • Families

  • Adults

To make an appointment with Sara, contact her online or call her +39 3457404660  

bottom of page